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Essential to Life

NIAGEN® is the only proven natural vitamin supplement shown to increase Nicotinamide Adenine Dinucleotide, also known as NAD+. Research shows that increasing your NAD+ levels may lead to age reversal in your cells, boosting your metabolism, enhancing mental focus, improving memory and even increasing energy. NIAGEN® has NDI status with the FDA.

IMPORTANT UPDATE: Due to high demand, we’ve created the MY NIAGEN® Membership Program. You’ll enjoy convenient, free monthly delivery and priority access to our limited inventory so you always have the benefits of NIAGEN® and even bigger savings.



  • Even bigger savings on NIAGEN®
  • Guaranteed availability and same
    low price.
  • Complete control. Pause and continue anytime.
  • Exclusive access to groundbreaking innovations.

Immortality is out of reach, but living more years with a body
that’s robust enough to make the most of them is a real possibility.


HPN Ultra is backed by a 60-day Money-Back Guarantee. If you aren’t completely satisfied with your purchase, it’s OK, send it back. We thrive on delivering satisfaction and results. Give us a call or email and we’ll go ahead and assist you on the return process.

Dr. David Leonardi

Dr. David Leonardi, MD

Founder of the Leonardi Executive Health Institute

In my 20+ years of medical history, I have never come across something so extraordinary as Niagen. Supplementing your body with Nicotinmaide Riboside not only restores NAD+ levels, but also promotes a surge of energy and mental clarity that taking Niagen every day is now my routine. *


Our team found that giving the chemical called NAD+ for just one week restored subject’s tissues, that would be akin to human 60-year-old’s cells becoming more like those belonging to a 20-year-old. 2

- Time News Article


Recent research suggests it may be possible to reverse mitochondrial decay with dietary supplements that increase cellular levels of a molecule called NAD+.3

- Scientific American

Customer Stories

Niagen has been working great in my life. My sister who suffers from fibromyalgia and arthritis just called this Saturday and told me that she doesn’t remember the last time she felt so great. She said that she wakes up now and feels energetic and wants to clean and organize her house and that is something she stopped doing many years ago. Her husband and daughters were the ones doing everything but now she has been up cooking and moving around, cleaning and back to being more independent. Right now I have my sisters and two friends on Niagen and of course ME. Thank you very much for your support. God will bless you and your company because for a fact you guys are on my prayer wall." - *

stars Zidnia Ayala, Los Angeles, CA These results are unique and to this individual. Results may vary due to a number of factors.

“I think that the nicotinamide riboside that is the only active ingredient in this product is an extremely important advance in anti-aging, though I'm skeptical of many of the ad-copy-like or placebo-effect-like comments. I'm reasonably confident that HPN is giving us an unadulterated product. HPN is definitely giving us the best deal in terms of how much you get for what you pay for. (I've done the math.) I think HPN is hyping the effects of nicotinamide riboside a bit too much. People contemplating a purchase should bear in mind that David Sinclair and Leonard Guarente say that you have to take 500 mg to 1000 mg a day to benefit from it (I would give you the link but Amazon doesn't like links). At 500 mg a day you would run through about two bottles a month. I personally think it is worth it." - *

stars Red M., Dallas, TX These results are unique and to this individual. Results may vary due to a number of factors.

"Perhaps it is my age (59). Or perhaps it is my health (diabetic). I had no idea how much I would benefit from this. I can actually work a full 40 hour week, and then put in 10 hours overtime! I am amazed, and I purchased several bottles as gifts for family who needs it as much as I did." - *

stars Belinda S., Grantsville, UT These results are unique and to this individual. Results may vary due to a number of factors.

"I have been using this for several months and notice a remarkable difference in the way I feel, my overall health, and my exercise endurance. This is most noticeable when I am lacking in sleep or when I am over-exerted. My energy level remains constant throughout the day. Only time will tell on the anti-aging properties, but I do believe my skin and hair have benefitted, and my hair has been growing faster since starting the product. I have also been using this in conjunction with my weight loss plan and have successfully lost a few pounds." - *

stars Cathy T., Los Angeles, CA These results are unique and to this individual. Results may vary due to a number of factors.

"I'm 63 and always looking for a boost ... I've tried ashwaganda, licorice and tianeptine, and so far Niagen seems to be better than the others for me." - *

stars Peter S., Orlando, FL These results are unique and to this individual. Results may vary due to a number of factors.

"I am not sure what is happening inside my body. I have noticed a definite increase in energy and endurance. Hope to see more evidence after completing the second bottle." - *

stars Victor M., Phoenix, AZ These results are unique and to this individual. Results may vary due to a number of factors.

"I am 62 years old, fell in love with strength training about 2 years ago and have been training hard (and having BIG fun) ever since. One of the things you discover on this journey is that there are myriad people/companies selling an endless number of supplements, most of which are marketing hype. Niagen® is an exception to this scenario. In a word this stuff is "ridiculous" ... as in extraordinarily effective and absolutely safe. I don't know how much difference it makes if your activity level is in the casual range. I do know (from my experience and others) that if you have anything like a passion for training, you will feel it in 3 ways: Faster recovery between sets, better recovery between workouts, and increased aerobic capacity." - *

stars E. Dunning, Newport Beach, CA These results are unique and to this individual. Results may vary due to a number of factors.

"Have only been taking this for a few days but already feel more energized and have more stamina. Can't wait to see what long term effects it may have with continued use." - *

stars Donna M., Chicago, IL These results are unique and to this individual. Results may vary due to a number of factors.

"This product is awesome! I have been having problems being completely tired by the time I get home from work and almost to the point of where j just can't function- this product has helped that! Not only is it a great product but the people behind the brand are great as well! I do not personally know them but have emailed them about questions and they always respond and are very helpful. This product is great to keep your mind focused and just all around good health! At least try it! Their website says 30 day money back if you don't like it." - *

stars Ashley G, Austin, TX These results are unique and to this individual. Results may vary due to a number of factors.

Frequently Asked Questions

What’s in NIAGEN®?

NIAGEN® is the first and only commercially available form of nicotinamide riboside (NR), a highly effective NAD+ booster and “no flush” form of vitamin B3 (niacin) that offers many health benefits *

Supplement facts
Serving Size: 2 Capsules
Servings Per Container: 30
Amount Per Serving %Daily Value**
Nicotinamide Riboside 250 mg *
*%Daily Value and/or Recommended Daily Intake not Established.
**Percent Daily Value is based on a 2,000 calorie diet.
Other Ingredients: Microcrystalline Cellulose,Cellulose (vegetarian capsule).

NiagenTM is a trademark of Chromadex®

Dietary Supplement 60 Capsules


To use NIAGEN®, take 2 capsules daily upon waking or immediately prior to consuming first meal. It is not necessary to take NIAGEN® with a meal. After each bottle, we recommend discontinuing usage for 3 days for maximum effectiveness.

What does NIAGEN® do?

To put it most concisely - NIAGEN® boosts our cellular NAD+ levels, which improves the function of our mitochondria and makes EVERY CELL in our entire body operate more efficiently. This enables our body to naturally reverse much of the aging process within our cells and results in an increase in metabolism, brain function, muschle endurance and overall health.

What will I “feel” when taking NIAGEN®?

Most users feel a heightened sense of mental clarity* as well as greatly increased all-day natural energy*. If you can imagine every one of the billion tiny cells in your body functioning on a higher level - that is the origination of the uplifting feeling that NIAGEN® provides.

Is NIAGEN® safe?

Each and every production run of NIAGEN® is tested by two independent agencies for label claim, heavy metal contamination, banned substances and adulteration. The main ingredient in NIAGEN®, call Nicotinamide Riboside, has extensive safety and effectiveness data backing its usage from a growing body of published scientific data. EVERYONE who is interested in long-term health and wellness, is recommended to take NIAGEN®.

Tons of research and a recent human study presented at the 4th Federation of American Societies for Experimental Biology (FASEB) Science Research Conference on NAD+ Metabolism and Signaling showed that NIAGEN® is completely safe to take. In fact, Niagen® is a naturally occurring vitamin B3 metabolite. Of course we recommend you talk your physician of you have any additional questions or if you are under any current medication. Your health comes first so it’s always best to be better informed. Link to Study >>

How do I use NIAGEN®?

To use NIAGEN® take (2) capsules daily upon waking up or immediately prior to consuming your first meal. It is not necessary to take NIAGEN® with a meal.

Is NIAGEN® different from other anti-aging supplements?

Yes. NIAGEN® is a proprietary ingredient and the only scientifically proven NAD+ booster on the market. NAD+ production is crucial to your age and well being. Science states that the communication breakdown between the cell nucleus and the mitochondria as the cause of aging. NIAGEN® restores that communication. No other product, including the negatively charged NADH, can increase your NAD+ levels like NIAGEN®.

Can I take NIAGEN®?

NIAGEN® has been tested for safety and is approved for anyone who is looking to increase their NAD+ levels. Of course, we’d recommend you contact your physician if you have any additional questions. A 2007 study published in Trends In Biochemical Sciences indicated that NIAGEN® safely increases (NAD+) levels without causing any harming side effects.

Learn More About NIAGEN®

It’s time to change your life for the better with NIAGEN®!
The only proven NAD+ Booster on the Market!


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