If you would like to know how a small group of Doctors and Scientist defied the laws of Aging
and then figured a way to make it available to you, me, and the rest of the general public,
then this is going to be the most interesting message you will ever read.
There’s a group of Bio-Geneticist based out of Southern California who have taken the initiative
to patent and produce what a Harvard Scientist calls “Essential to Life” and may very well
be the next step in human evolution. And this is no ordinary Scientist. This is Dr. David
Sinclair, Co-Director of the Paul F. Glenn Laboratories for the Biological Mechanisms of
Aging at Harvard Medical School. Sinclair is considered one of TIMES Magazine “Most Influential
People in the World”.
Dr. Sinclair, an expert in human genetics and cellular function, discovered a link to
aging and degenerative disease and the secret weapon to reversing it. He and his team
took a closer look into our cells and determined that as we age, our cells become less
and less efficient due to the lack of a very important and essential metabolite called NAD+.
Low levels of NAD+ cause you to feel less energized, less focused, excess mental fog and mental
loss, excess weight gain especially in your mid section and other issues and illnesses related
to aging. This is commonly known as mitochondrial dysfunction.
WHAT IS NAD+
NAD+ is an important metabolite found in all human cells that has recently shown to
restore mitochondria functionality and vitality1. “NAD+ levels tend
to drop by as much as 50% as we get older”, according to Dr. David Agus a world
leading Physician in Cancer treatment and a pioneer in Biomedical Research. Above all, NAD+
cannot be taken like other vitamins because it does not survive the digestive system long
enough to enter your cells, making it extremely difficult to supplement your NAD+ levels.
Sinclair concluded that higher NAD+ levels promote cells to behave younger and more vibrant.
Studies show that high levels of NAD+ result in stronger, healthier cells and mitochondrial
function. In fact, one study resulted in Sinclair publishing a ground-breaking paper which
found that introducing NAD+ to the cell resulted in the “equivalent of a human 60 year old
becoming more like a 20 year old”, claiming “we went straight back to being young again”2.
More importantly, their analysis revealed that in its initial stages, mitochondrial dysfunction
is reversible with NAD+ supplementation, enabling the life and health of cells to be prolonged
at the molecular level.
Now imagine feeling like you’re 30 again and having the energy to
go out and meet new people, having the strength to exercise and look great every single day.
Imagine if the cells in your brain were restored to regain their cognitive abilities or if
the cells in your eyes performed like never before, to even restoring the cells in your skin
and muscles to appear and perform like they did in their youth. All these amazing benefits
may now be available to you.
According to Dr. David Sinclair of Harvard University, Dr. Anthony Sauvé of Cornell University,
and thousands of other physicians, including myself belief you can do this by restoring your
NAD+ levels. “If we could restore lost NAD+, aging cells might behave as if they were younger.
Immortality is out of reach but living more years with a body that’s robust enough to make
the most of them is a real possibility” says Dr. David Agus.
In fact, there’s an extensive amount of research to back up this claim.
My name is Dr. David Leonardi MD. I am a diplomat for the American Board of Anti-Aging Medicine,
a certified Nutrition Specialist by the American College of Nutrition, and a Professional
member of the American Diabetes Association. I graduated from the University of Miami School
of Medicine and received my residency in emergency medicine at the University of California,
San Francisco. I have been practicing the science of vitality and longevity medicine exclusively
for 20 years now and just about every day I get the same question from many of my new patients;
why do I feel so old?
THE FUNCTION OF MITOCHONDRIA
Mitochondria has been determined to play one of the most important roles. Mitochondria are
specialized organelles found in your cells, which perform important functions related to
converting nutrients such as fats, proteins, and carbohydrates into energy. They are responsible
for your cellular respiration and make up about 10% of your body weight. About 70% of the energy
you produce goes to keeping your organs running in the background; like your heart and lungs. So
in other words, your Mitochondria produce the energy that keeps you alive.
Researchers warn that unhealthy mitochondrial may lead to an array of degenerative illnesses,
ranging from diabetes and neurological disorders to heart failure . Mitochondria undergo a
complex series of biochemical transformations that generate energy. This energy-intensive process
results in a constant exposure to free radicals—and rendering the mitochondria especially vulnerable
to oxidative damage. The result is a cellular breakdown: the mitochondria gradually deteriorate,
leading to a decrease in vital energy production and a deadly increase in free radical generation.
Over time, this continuous free-radical onslaught destroys the mitochondria through progressive membrane damage and molecular decay. As levels of oxidative damage from mitochondrial dysfunction steadily rise, the body’s antioxidant defenses gradually weaken at the same time, accelerating cellular dysfunction and death. This fatal cycle speeds the general decline in overall body function and contributes to the beginning of degenerative disease.
Researchers have also reported that inefficient mitochondria increase your chances of reaching obesity, the disease brought and perpetuated by the vicious cycle of excess weight and body fat gain. Because your mitochondria are responsible for metabolizing nutrients like carbs and fat, disruptions can trigger your body into fat storage mode. This is why weight is such an issue amongst older individuals and why weight loss seems almost impossible.
Recent studies have demonstrated that healthy Mitochondria play a broader role in protecting
us against a wide range of adverse health conditions. When our mitochondria function correctly
there is a reduced risk for the development and spread of certain illnesses within our cells
and within our bodies.
According to Dr. Anthony Sauvé, “Mitochondrial decline is the hallmark of many diseases associated
with aging, such as cancer and neuro-degeneration”. In addition, a recent study conducted by
the American Geriatrics Society showed that more than “40% of adults 60 years of age and older
have a combination of risk factors known as metabolic syndrome, which puts people at
increased risk for developing diabetes, cardiovascular disease, and even certain cancers"3.
A 2010 study determined nearly 40 percent of men and women born today will be diagnosed
with cancer at some time during their lifetime. Considering that cancer is sometimes referred
to as Mitochondrial Disease, cellular health has now become the
most important factor to consider by many physicians.
SUPPLEMENTING YOUR NAD+
NIAGEN® is a proprietary ingredient also known as Nicotinamide Riboside or NR for short. NIAGEN® is the only proven metabolite shown to boost NAD+ levels and the best part it’s a naturally occurring vitamin B3, so it is completely safe4. Unlike standalone NAD+, NIAGEN® can be ingested orally. It enters your body to be converted into NAD+ surviving your digestive system. NIAGEN® has been proven to elevate NAD+ levels within 8 hours of ingestion providing a surge of energy and noticable mental clarity5.
What is Nicotinamide Riboside?
Nicotinamide Riboside is a pyridine-nucleoside form of vitamin B3 that functions as a precusor to nicotinamide adenine dinucleotide or NAD+. Nicotinamide Riboside is naturally found in food, such as milk but the body does not get enough of it, especially as we age and NAD+ levels naturally decline.
A 2015 study showed a single 100mg dose of Nicotinamide Riboside was effective in raising NAD+ levels by 30%; 300mg and 1000mg dosages showed a 50% increase in NAD+ levels. The increase in NAD+ levels were longer lasting at the higher dosages. NIAGEN® is the only proven dietary supplement shown to elevate NAD+ levels making the most reviewed and essential supplement on the market today.
The benefits of restoring NAD+ levels are:
- Optimized Mitochondrial Function1
- Improve Metabolism6
- Cardiovascular Health7
- Mental Clarity and Focus8
- Heightened Energy Level9